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Florida Keys Road Trip: 10 Must-See Stops on the Overseas Highway

The 165 mile drive between Miami and Key West is without a doubt one of the most iconic road trips in the US, and if you’ve had the privilege of driving this epic route, then you know why! You could spend weeks trying to do, see, and eat everything along the way! Unfortunately, many people (ourselves included) only have a day or two to squeeze in as much as they can. For that reason, we’ve put together what we think are the 10 must-see stops along the way to help you make the most of your time on Florida’s Overseas Highway!

Be sure to check out our “Florida Keys Road Trip: Miami to Key West in a Day” travel vlog for a closer look at our experience!

:: From Miami International Airport, your first stop will be a 40 min (35 mi) drive ::

1. Robert is Here Fruit Stand (19200 SW 344th St, Homestead, FL)

Robert is Here Fruit Stand is a family-owned market selling local & exotic fruits and veggies, and more importantly… MILKSHAKES! But don’t let the name “Fruit Stand” fool you. This place has a full kitchen, a huge selection of snacks and local goods, as well as a feeding/petting zoo which includes a giant tortoise and even an emu!

:: 35 min (30 mi) drive ::

2. Mrs. Mac’s Kitchen (99336 Overseas Hwy, Key Largo, FL)

Jeff MacFarland opened Mrs. Mac's Kitchen in 1976 in honor of his mother and her recipes. Today, nearly 5 decades later, Mrs. Macs is a staple in the Key Largo community, and still serves up some of the best fresh seafood and Key Lime Pie you can find! We personally loved the Key Lime Freeze! It’s like drinking a frozen Key Lime Pie! So good!

:: 23 min (18 mi) drive ::

3. Florida Keys Brewing Co. (81611 Old Hwy, Islamorada, FL)

Florida Keys Brewing Company is the Upper Keys first microbrewery and offers a selection of crowd favorites as well as a rotating list of seasonal and barrel-aged beers, on draft. Just remember that you’ve still got another 80 miles to drive, so it’s probably good to practice the one-and-done policy, or have a designated driver!

:: 7 min (4.5 mi) drive ::